The sporebiotics assessed in the clinical trial were Bacillus coagulans MY01 and Bacillus subtilis MY02. Other benefits including a longer shelf life and lower CFU of bacteria required to be added into the product. ![]() The bacterium is resistant to heat and pH changes, allowing it to survive stomach acid and reach the intestines, in turn modulating the gut microbiome. ![]() The trial assesses sporebiotics from the Bacillus genus, which Dybajlo pointed out was a bacterium that forms spores naturally. The company has conducted its first human clinical trial with Universitaire Ziekenhuizen Leuven in Belgium to assess the benefits of sporebiotics when used with PPI medications. “We are not against the PPI medications, we need the medications, but if one were to need it in the long term, they can use it with our probiotics as an add-on therapy ,” Dybajlo said. “PPI medications could be used to reduce stomach acid, but it can cause shift in the microbiome, such as an overgrowth of the bacteria streptococcus in the small intestines and this could increase risk for gastroenteritis in the long term. Proton pump inhibitor medications include examples such as omeprazole, which is a medication prescribed to reduce gastric acid in patients suffering from indigestion and acid reflux etc.ĭybajlo noted that while such medications were important and beneficial, long term use for more than eight weeks could cause side effects that could worsen the condition. Its newly launched product, known as My Gastric, aims to tackle gut dysbiosis and side effects such as small intestinal bacterial overgrowth (SIBO) caused by the long-term use of proton pump inhibitor (PPI) medications. Working with pharmacies and healthcare professionals is already the mode of operation for the company in the domestic Belgium market, as well as its other existing markets, including Germany and the Baltic states. Speaking to NutraIngredients-Asia, CEO Raf Dybajlo, said that the expansion plan would focus on working with key opinion leaders, such as specialist doctors, in introducing the sporebiotics as an add-on to medical therapies. The gut-brain axis: Psychobiotic opportunity in 25 countriese.Uncovering white spaces – Probiotics for a smooth menopause transition.Uncovering White Spaces – Probiotics for Pets. ![]()
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